Diagnostic Departments

Biochemistry

The Department is fully automated with state of the art, high throughput analysers which employ contemporary methodologies for all testing. The Department has the capacity to produce in excess of 6000 test results per hour and the analysers are directly interfaced with the Laboratory Information System.

The Clinical Biochemistry Department offers a comprehensive range of testing in areas of routine general chemistry, specific protein chemistry, urine drug screening, endocrinology, tumour markers, allergy and antenatal screening for Down’s Syndrome.

The majority of analyses are performed as samples arrive, however there are some lower volume and more esoteric tests which are performed only on selected days. As many of the reference ranges quoted against results are age and gender specific, it is important to note the date of birth and sex of the patient on the requestform.

Cytology

Cytology is the study of cells which incorporates Gynaecological, Non-Gynaecological and Fine Needle Aspirate Cytology. 

This study involves the detection of precancerous and cancerous cells taken from different parts of the body. 

The services provided by our Cytology Department are:

  • Pap Smear screening which include liquid-based Pap smear testing(SurePath)
  • Non-Gynaecological Cytology
  • Fine Needle Aspiration (FNA) services
  • HPV DNA testing

To maintain high quality Cytology services, full-time qualified and experienced Pathologists and Cytotechnologists have been recruited. 
 
Our Cytotechnologists hold post-graduate qualifications in Cytopathology, either the Cytotechnology Certificate of the International Academy of Cytology CT(IAC) or the Cytotechnology Certificate of the Australian Society of Cytology CT(ASC). 
 
Emphasis on Quality Control, Quality Assurance, cost effectiveness and continuing education is the hallmark of our Cytology Department.

Histopathology

Histopathology is the microscopic study of organs and tissues that has been surgically removed to make the diagnosis. It involves specialised preparation of pieces of human tissue that is viewed under a microscope by qualified and experienced pathologists. 
 
These tissue samples are obtained from a wide range of sources including operating theatres, endoscopy and colposcopy units, outpatient clinics and GP surgeries.

Surgical, anatomical and consultative pathology services are available through our pathologists in the Department of Pathology. The Histopathology services we offer include:

  • Routine haematoxylin & eosin staining
  • Special histochemical staining
  • Immunohistochemistry
  • Molecular pathology

The Immunohistochemistry combines immunological, histological and biochemical techniques to identify tissue components by the interaction of target antigen with specific antibody (marker) tagged with chromogen.

  • IHC platform-automated machine with a capacity of running 20 slides over a four hour cycle.
  • Turn around time of IHC is 3 to 7 days.

Epithelial, mesenchymal, melanocytic, lymphoid and germ cell markers are routinely used in our laboratory in tumour diagnosis.

Immunohistochemistry helps in

  • dectecting the primary site of metastatic tumour.
  • histogenesis of an undifferentiated malignant neoplasm.
  • prognostication of a malignant tumour (ER,PR,Cerb-2, etc)
  • differentiating certain benign tumours from malignant tumour.
  • immunophenotyping of lymphoma.

Molecular diagnostic work is perfomed in selected areas like lung cancer and intestinal cancer in collaboration with Australian laboratory.

Haematology

The Haematology Department performs a wide range of tests from basic blood cell count to routine and special coagulation assays, bone marrow examinations, haemoglobin analysis and blood bank services.

The Full Blood Count is performed on our automated haematology analyser which provides information on the quantity and quality of platelets, red and white blood cells. This information aids in the diagnosis of conditions such as anaemia, thalassaemia, leukaemia and infections, particularly dengue.

Based on the results obtained and clinical history of the patient, a blood film is made and reviewed under the microscope for final reporting by a trained scientist.

Selected film with significant abnormal results or blood film finding is then referred to our Consultant Haematologist for confirmation.

Our Coagulation Section provides services to access patient’s haemostasis status which is particularly important for patients on anticoagulant therapy. Besides that, special coagulation tests like Lupus Anticoagulant, Protein C, Protein S, Antithrombin III, Factor V Leiden, Factor VIII and Factor IX are also available to assess congenital and acquired coagulopathies. These tests are performed on selected days.

The Blood bank Section performs blood grouping and checks the presence of antibodies in patients. Transfusion services are only offered to centres under a service agreement.

Microbiology

The Microbiology Department performs a wide variety of microbiological testing including Bacteriology, Mycology, Mycobacteriology, Parasitology, Serology/ Immunology, Molecular Diagnostics and Environmental testing.

Microbiology culture employs the conventional methods with current technology to isolate the causative agent of infection. Accurate and relevant results in microbiology depend on both the doctor and the laboratory. Submission of the best specimen type for a particular test or recovering a specifi c microorganism is of paramount importance for a successful outcome.

Factors contributing to the successful isolation of potential pathogens include specimen selection, quality, collection, and transportation to the laboratory.

Relevant clinical information is also needed to help the laboratory in processing the specimen optimally. Recent, current or intended antimicrobial treatment should be indicated to help the microbiologist interpret test results and help in the selection of antimicrobial to be tested.

The Immunology and Serology section provides services mainly for Autoimmune Serology, Infectious Disease Serology and Sexually Transmitted Diseases.

Water sample testing includes Total plate count, Total coliform and Faecal (E.coli) coliforms. Swabs are tested for bacterial and fungal growth. Air quality testing is performed using the open plate method for detecting both bacteria and fungal growth.

Molecular Diagnostics

The Molecular Diagnostics section provides services for detection of infectious diseases using polymerase chain reaction. Test includes STDs (Chlamydia & Gonorrhea, Human papillomavirus), M. tuberculosis complex, Alpha thalassaemia (SEA type), Influenza A/H1N1 pandemic, quantitation of HIV-1 RNA, Hepatitis B DNA and Hepatitis C RNA and HCV genotype. These tests are performed on selected days.

 

 

 

Copyright © 2007 - 2018 Gribbles Pathology (M) Sdn Bhd. All Rights Reserved.

Powered by CORNERSTONE CONTENT MANAGEMENT SYSTEM